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Products

API Intermediates
 
  • COMMERCIALIZED

    Name Of The IntermediateChemical Structure
    Abacavir sulphate

    N-(2-Amino-4,6-dichloro-5-pyrimidinyl) formamide

    Abacavir-sulphate

    N-(2-Amino-4,6-dichloro-5-pyrimidinyl) formamide

    Candesartan Cilexetil

    Methyl 3-((2'-(2H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-ethoxy- 3H-benzo[d]imidazole-4-carboxylate[CS-VI (Tetrazole)] CAS #124750-51-2

    3-((2'-(2H-Tetrazol-5-yl)biphenyl-4-yl)methyl)-2-ethoxy-3H- benzo[d]imidazole-4-carboxylic acid [CS-VII (Acid)] CAS #139481-59-7

    2-Ethoxy-3-((2'-(2-trityl-2H-tetrazol-5-yl)biphenyl-4-yl)methyl)-3H-benzo[d]imidazole-4-carboxylic acid [CS-VIII (Trityl Candesartan)] CAS #139481-72-4

    1-(Cyclohexyloxy carbonyloxy) ethyl 2-ethoxy-3-((2'-(2-trityl-2H-tetrazol-5-yl) biphenyl-4-yl)methyl)-3H-benzo[d]imidazole-4-carboxylate [CSC-I (Trityl Candesartan Cilexetil)] CAS #170791-09-0

    Carvedilol

    4-(2,3-Epoxypropoxy)carbazole CAS # 51997-51-4

    Citalopram HBr / HCl / Escitalopram Oxalate

    4-[4-(Dimethyl amino)-1-(4-fluorophenyl)-1-hydroxybutyl]-3-(hydroxyl methyl) benzonitrile (Cyano diol) CAS #90357-53-2

    Various salts of Cyano Diol Compound HCl / HBr/Phosphate

    1-(4-Fluorophenyl)-1,3-dihydroisobenzofurane-5-carbonitrile CAS #64169-67-1

    (3-[5-Cyano-1-(4-fluorophenyl) (1,3-dihydroisobenzofuranyl)] propyl) dimethylamine oxalate (Citalopram oxalate from 5-cyanophthalide route) CAS # 21986-08-2

    4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxy-1-butyl-3-hydroxymethyl-benzonitrile hemi -(+)-di-p-toluoyl-d-tartaric acid salt

  • COMMERCIALIZED

    Name Of The IntermediateChemical Structure
    Clopidogrel bisulphate

    4,5,6,7-Tetrahydrothiopheno[3,2-c] Pyridine HCl (from Route-I)
    CAS #28783-41-7

    Racemic methyl. alpha.-(4,5,6,7-tetrahydro-5-thieno[3,2-c]pyridyl) (2-chlorophenyl)acetate HCl (from Route-I)

    2-Bromo-2-(2-chlorophenyl)acetic acid methyl ester (from Route-I)
    CAS #85259-19-4

    (S)-Methyl 2-(2-chlorophenyl)-2-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetate (7,7-dimethyl-2-oxobicyclo[2.2.1]heptane-1-yl)methanesulfonate (from Route-I)
    CAS #120202-68-8

    D(+)-Chloro phenyl glycine methyl ester (from Route-II)
    CAS #141109-17- 3

    2-Thiophene ethanol tosyl ester (from Route-II)
    CAS #40412- 06 – 4

    Gabapentin HCl

    2-[(Aminomethyl) cyclohexyl] acetic acid HCl
    (Gabapentin HCl)

    1,1-Cyclohexane diacetic acid monoamide
    CAS # 73590-58-6

    Hydrochlorothiazide

    4-Amino-6-chlorobenzene-1,3-disulfonamide
    CAS #121-30-2

    Itraconazole

    4-[4-[4-(4-Hydroxy phenyl) piperazinyl]phenyl]-1-(methyl propyl)-1,2,4-triazole-5-one (Itraconazole hydroxy)
    CAS # 8984821-5

    Cis-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazole-1-yl methyl)-1,3-dioxane-4yl methyl methane sulfonate (Itraconazole sulfonate)
    CAS # 67914-86-7

    Lamivudine

    (2R-Cis)-5-(4-Amino-1,2-dihydro-2-oxo-l-pyrimidinyl)-1,3-oxathiolane-2-carboxylic acid (2S, 5R)-menthyl ester (CME Compound)
    CAS #73590-85-9

    Lamivudine salicylate
    CAS # 173522-96-8

  • COMMERCIALIZED

    Name Of The IntermediateChemical Structure
    Lansoprazole

    2-Hydroxy methyl-3-methyl-4-(2,2,2-trifluoroethoxy)pyridine (Lansoprazole hydroxy base/HCl salt)
    CAS #103577-66-8

    2-Chloromethyl-3-methyl-4-(2,2,2,-trifluoroethoxy) pyridine HCl (Lansoprazole Chloro)
    CAS #127337-60-4

    2-[[[3-Methyl-4-(2,2,2-trifluoro-ethoxy)-2-pyridinyl]methyl]thio]-1H-benzimidazole (Lansoprazole Sulphide)
    CAS #103577-40-8

    Losartan potassium

    2-Cyano-4'-bromo methyl biphenyl (Bromo OTBN)
    CAS #114772-54-2

    N-(triphenyl methyl)-5-(4'-bromo methyl biphenyl-2-yl)tetrazole (TTBB)
    CAS #124750-51-2 / 133051- 88 - 4

    2-(4-{[2-Butyl-4-chloro-5-(hydroxymethyl) imidazolyl]methyl} phenyl)benzene carbonitrile
    CAS #114772-55-3

    2-Butyl-4-chloro-1-[2'(2-trityl-2H-tetrazol-5-yl)biphenyl-4-ylmethyl]-1H-imidazol-5-ylmethanol (Trityl Losartan)
    CAS #133909-99-6

    Montelukast

    Methyl-2-(3-(3-(2-(7-chloro-2-quinolinyl)ethenyl)phenyl)-3-oxypropyl)benzoate (Route-II) CAS #149968 - 11 - 6

    Methyl-2-(2-(3(S)-(3-(2-(7-chloro-2-quinolinyl)ethenyl)phenyl)-3-hydroxy propyl)phenyl)benzoate (Route-II)
    CAS #181139-72-0

    2-(2-(3(S)-(3-(2-(7-Chloro-2-quinolinyl)ethenyl)phenyl)-3-hydroxy propyl)phenyl)-2-propanol(Route-II)
    CAS #142569-70-8

    2-(1-(mercaptomethyl) cyclopropyl) acetic acid
    CAS #162515-68-6

    Omeprazole

    2-Hydroxymethyl-4-methoxy-3,5-dimethyl pyridine HCl (Omeprazole hydroxyl HCl)

    2-Chloromethyl-4-methoxy-3,5-dimethyl pyridine HCl (Omeprazole chloro)
    CAS #86604-75-3

    5-Methoxy-2[[(3,5-dimethyl-4-methoxy pyridinyl) - methyl] thio]-1H-benzimidazole (Omeprazole sulphide)
    CAS #73590-85-9

    Pantoprazole

    5-(Difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)-methyl]thio]-1H-benzimidazole (Pantoprazole Sulphide)
    CAS # 102625-64-9

  • COMMERCIALIZED

    Name Of The IntermediateChemical Structure
    Pioglitazone HCl

    (Z)-5-(4-(2-(5-Ethylpyridin-2yl) ethoxy) benzylidene) thiazolidine-2,4-dione
    CAS #144809-28-9

    (Z)-5-(4-(2-(5-Ethylpyridin -2yl)ethoxy) benzylidene) thiazolidine-2,4-dione HCl

    5-(4-(2-(5-Ethylpyridin-2-yl)ethoxy)benzyl)thiazolidine-2,4-dione
    CAS #111025-46-8

    Rabeprazole Sodium

    2-Hydroxy methyl-3-methyl-4- (3-methoxy propoxy)pyridine HCl (Rabeprazole hydroxy HCl)
    CAS #118175-10-3

    2-Chloro methyl-3-methyl-4-(3-methoxy propoxy)pyridine HCl (Rabeprazole chloro)
    CAS #153259-31-5

    2-[[[4-(3-Methoxy-propoxy)-3-methyl-2-pyridinyl]methyl]thio]-1H-benzimidazole (Rabeprazole sulphide)
    CAS #117977-21-6

    Risperidone

    6-Fluoro-3-(4-piperidinyl)-1,2-benzisoxazole
    CAS #84163-77-9

    6-Fluoro-3-(4-piperidinyl)-1,2-benzisoxazole HCl
    CAS #84163-13-3

    3-(2-Chloroethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
    CAS #63234-80-0

    3-(2-Chloroethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one HCl
    CAS #93076-03-0

    Sertraline HCl

    Cis-[4-(3,4-Dichlorophenyl) (1,2,3,4-tetrahydro naphthyl)] methylamine HCl (Racemic Sertraline)
    CAS #79617-89-3

  • COMMERCIALIZED

    Name Of The IntermediateChemical Structure
    Sibutramine HCl

    1-(1-(4-Chlorophenyl) cyclobutyl)-3-methylbutan-1-amine fumarate

    Sildenafil Citrate

    4-Nitro-1-methyl-3n-propyl pyrazole-5-carboxamide (Sildenafil Amide)
    CAS # 139756-01-7

    4-Amino-1-methyl-3n-propylpyrazole-5-carboxamide (Sildenafil Amine)
    CAS #139756-02-08

    4-[(2-Ethoxyphenyl) carbonylamino]-1-methyl-3n-propylpyrazole-5-carboxamide (Sildenafil Coupled)
    CAS #139756-03-09

    5-(2-Ethoxyphenyl)-1-methyl-3n-propyl-6-hydropyrazolo[4,5-d]pyrimidine-7-one (Sildenafil cyclised)
    CAS # 139756-21-1

    5-(5-Chlorosulfonyl-2-ethoxyphenyl)-1-methyl-3n-propyl-1,6-dihydro-7H-pyrazolo-[4,3-d]-pyrimidin-7-one (Sildenafil chlorosulfonyl)
    CAS #139756-22-2

    5-{2-Ethoxy-5-[(4-methylpiperazinyl)sulfonyl]phenyl}-1-methyl-3n-propyl-6-hydropyrazolo[4,5d]pyrimidine-7-one [Sildenafil]
    CAS #139755-83-2

    Sumatriptan Succinate

    (3-(2-Aminoethyl)-1H-indol-5-yl)-N-methyl methanesulfonamide (Suma Amine)

    Valsartan

    Benzyl (2S)-2-amino-3-methyl butanoate (L-valine benzyl ester)

    L-valine methyl ester HCl
    CAS # 6306-52-1

    2-[(2'-Cyano-biphenyl-4-ylmethyl)-amino]-3-methyl-butyric acid benzyl ester

    3-Methyl-2-(N-((2'-(2-trityl-2,5-dihydro-1H-tetrazol-5-yl)biphenyl-4-yl)methyl)pentanamido)butanoic acid (Trityl valsartan)
    CAS # 195435-23-5

    (S)-Methyl 2-((2'-cyanobiphenyl-4-yl)methylamino)-3-methylbutanoate
    CAS # 37863-89-9

    (S)-Methyl 2-(N-((2'-cyanobiphenyl-4-yl)methyl)pentanamido) -3-methylbutanoate
    CAS # 137863-90-2

  • COMMERCIALIZED

    Name Of The IntermediateChemical Structure
    Venlafaxine HCl

    2-(1-Hydroxycyclohexyl)-2-(4-methoxyphenyl)acetonitrile [VH-I (Nitrile)]

    1-(2-Amino-1-(4-methoxyphenyl) ethyl)cyclohexanol HCl [VH-II (Amine)]
    CAS # 149289-31-6

    INTERMEDIATES READY FOR COMMERCIAL SCALE UP

    Almotriptan

    (4-Nitrophenyl)methanesulfonyl chloride CAS #4025-75-6

    3-((Pyrrolidin-1-ylsulfonyl) methyl)benzeneamine

    N-(4-((pyrrolidin-1-ylsulfonyl)methyl) phenyl)methanediamine HCl

    2-(5-((Pyrrolidin-1-ylsulfonyl)methyl)-1H-indol-3-yl)ethanamine

    Amlodipine Besilate

    Phthaloyl Amlodipine CAS #88150-62-3

    Atomoxetine HCl

    3-Chloro-N,N-dimethyl-3-phenylpropan-1-amine hydrochloride

    N,N-Dimethyl-3-phenyl-3-(o-tolyloxy)propan-1-amine oxalate

    Atorvastatin Calcium

    2-(2-(4-Fluorophenyl)-2-oxo-1-phenylethyl)-4-methyl-3-oxo-N-phenylpentanamide (Diketo)

    tert-Butyl 2-(3-amino-2-oxo-2,3,4,5-tetrahydrobenzo[b]azepin-1-yl)acetate

    tert-Butyl-3-(S)-amino-2,3,4,5-tetrahydro-1H-[1]-benzo[b]azepin-2-one-1-yl)acetate

  • INTERMEDIATES READY FOR COMMERCIAL SCALE UP

    Name Of The IntermediateChemical Structure
    Duloxetine HCl

    3-(Dimethylamino)-1-(2-thienyl)propan-1-ol

    (1R)-3-(Dimethylamino)-1-(2-thienyl)propan-1-ol mandelate
    CAS # 287737-72-8

    Irbesartan

    2-N-Butyl-4-Spirocyclopentane-1-[(2'-(Triphenyl-methyl tetrazol-5-yl) Biphenyl-4-yl) methyl]-2-imidazolin-5-one (Trityl Irbesartan)
    CAS #138402-10-5

    Levocetirizine dihydrochloride

    (4-Chlorophenyl) (phenyl)methanamine

    N,N-Bis(2-chloroethyl)-4-methylbenzenesulfonamide

    (R)-1-((4-Chlorophenyl)(phenyl) methyl)piperazine

    Lisinopril

    N6-(Trifluoroacetyl) -L-lysyl-L-proline
    CAS #103300-89-6

    N2-(1-(S)-ethoxycarbonyl-3-phenylpropyl)-N6-(trifluoroacetyl)-L-lysyl-L-proline
    CAS #103300-89-6

    Losartan

    2-Butyl-4-chloroimidazole-5-carbaldehyde (BCFI) CAS # 99189-60-3

    Montelukast

    2-(1-(mercaptomethyl) cyclopropyl) acetic acid
    CAS # 162515-68-6

  • INTERMEDIATES READY FOR COMMERCIAL SCALE UP

    Name Of The IntermediateChemical Structure
    Montelukast

    5-Methyl-2-[(2-nitrophenyl)amino]thiophene-3-carbonitrile
    CAS #138564-59-7

    2-Methyl-10H-benzo[b]thio pheno[3,2-f]1,4-diazepine-4-ylamine HCl
    CAS #138564-60-0

    Quetiapine hemifumarate

    Dibenzo [b,f][1,4]thiazepin-11(10H)-one
    CAS #3159-07-7

    11-Piperazinyl-dibenzo[b,f][1,4] thiazepine dihydrochloride

    Quinapril

    Phenylmethyl(3R)-1,2,3,4-tetrahydroisoquinoline-3-carboxylate

    Maleate salt of Quinapril benzyl ester

    Ramipril

    2-Azabicyclo[3,3,0]-octane-3-carboxylic acid HCl

    (±)Benzyl,endo-CIS-2-azabicyclo[3.3.0]-octane-3-carboxalate mono hydrochloride
    CAS #93779-29-4

    (3S)Benzyl,endo-CIS-2-azabicyclo [3.3.0]-octane-3-carboxalate hydrochloride
    CAS #93779-31-8

    Rizatriptan

    4-((1H-1,2,4-Triazol-1-yl)methyl)benzenamine

    (4-[1,2,4] Triazol-1-yl methyl phenyl) hydrazine

    Rosiglitazone Maleate

    5-(4-(2-(Methyl(pyridin-2-yl)amino) ethoxy) benzylidene) thiazolidine-2,4-dione
    CAS # 122320-74-5

  • INTERMEDIATES READY FOR COMMERCIAL SCALE UP

    Name Of The IntermediateChemical Structure
    Telmisartan

    Methyl 4-butyramido-3-methyl-5-nitrobenzoate

    7-Methyl-2-propyl-3H-benzo[d]imidazole-5-carboxylic acid

    1,4'-Dimethyl-2'-propyl-2,6'-bi(1H-benzo[d]imidazole)

    Methyl 4'-((1,4'-dimethyl-2'-propyl-2,6'-bi(1H-benzo[d]imidazol)-1'-yl) methyl)biphenyl-2-carboxylate (Methyl ester)

    2-(2-Ethoxy phenoxy)ethyl bromide
    CAS #3259-3-8

    Zidovudine

    5-O’ Trityl thymidine

    5-O-Trityl-2,3-anhydro thymidine

    Trityl Zidovudine

    Zolmitriptan

    Methyl-2-amino-3-(4-nitrophenyl)propanoate (Zolmi Methyl ester)

    Methyl-2-(ethoxycarbonylamino) -3-(4-nitrophenyl)propanoate (Zolmi Propanoate)

    (S)-4-(4-Aminobenzyl)oxazolidin-2-one (Zolmi Oxazolidin)
    CAS #17155-0-12-2

    Fexofenadine HCl

    Methyl 2-(4-(4-(4-(hydroxydiphenylmethyl)piperidin-1-yl)butanoyl)phenyl)-2-methylpropanoate

    Methyl 2-(4-(1-hydroxy-4-(4-(hydroxydiphenylmethyl)piperidin-1-yl)butyl)phenyl)-2-methylpropanoate

    Stavudine

    3',5'-Di-O-methanesulfonyl-2,2'-anhydro-5-methyluridine

    5'-Benzoyl-2',3'-didehydro-3'-deoxythymidine

 
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